Minggu, 25 Maret 2012

[I520.Ebook] PDF Download Adenosine: A Key Link between Metabolism and Brain ActivityFrom Springer

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Adenosine: A Key Link between Metabolism and Brain ActivityFrom Springer

Homeostasis of key metabolites and metabolic health affects all bodily systems.  Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders.  Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions.  Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition. 

Adenosine:  A Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system.  Because of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism.  At the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression.  Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function.  Leaders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders.  This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.

  • Published on: 2012-08-30
  • Released on: 2012-08-30
  • Format: Kindle eBook

Review

From the book reviews:

“This textbook catalogues the debate concerning adenosine metabolism and it’s possible role in ischemia, trauma, and epilepsy animal models. … I do recommend this book to cerebral ischemia researchers.” (Joseph J. Grenier, Amazon.com, August, 2014)

From the Back Cover

Homeostasis of key metabolites and metabolic health affects all bodily systems.  Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders.  Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions.  Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition. 

Adenosine:  A Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system.  Because of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism.  At the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression.  Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function.  Leaders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders.  This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.

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0 of 0 people found the following review helpful.
CNS Adenosine in Trauma, Ischemia, & Epilepsy
By Joseph J Grenier
CNS Adenosine

Springer New York Berlin Heidelberg

Joseph J Grenier MD PhD

This textbook catalogues the debate concerning adenosine metabolism and it’s possible role in ischemia, trauma, and epilepsy animal models. We should use MR spectroscopy to help substantiate many of the animal research findings. This is yet another argument for and against to a certain degree. I do recommend this book to cerebral ischemia researchers. Translational Ischemia Research should however be continued. ATP, GTP and the cytosolic cyl mediators should be looked for in the same brain sections. Penumbra research should continue in this area.

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Jumat, 23 Maret 2012

[A453.Ebook] PDF Download The Danger Artist (Kindle Single) (GQ Books), by Wyatt Mason

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The Danger Artist (Kindle Single) (GQ Books), by Wyatt Mason

The artist Ai Weiwei -- photographer, architect, gambler, orchestrator of installations, organizer of happenings, troublemaker and tweeter -- is one of China's most outspoken dissidents. He has continually tested the bounds of free speech and in the Spring of 2011, Beijing officials took the dare. Since June, he has remained under virtual house arrest, forbidden from blogging, tweeting and giving interviews to the foreign press. That did not stop GQ's Wyatt Mason from trying to pay him a visit.

  • Sales Rank: #929362 in eBooks
  • Published on: 2011-12-05
  • Released on: 2011-12-05
  • Format: Kindle eBook

Amazon.com Review
Meet Ai Weiwei, China's most dangerous man. If you don't know about Ai yet, don't worry. You're not alone. Ai Weiwei is both very famous and very hard to pin down, a modern Chinese artist of international renown whose art you cannot find on display in China. A blackjack guru, photographer, dissident, architect, cultural critic, and high-volume tweeter. He is also a man who, on April 3, 2011, was whisked away by Chinese authorities and disappeared for 81 days. Wyatt Mason, a contributing writer for the New York Times Magazine and a contributing editor at Harper's, goes to China to track down Ai, but finds himself struggling, though a stifling, smog-laden Beijing summer, to find someone who will even mention him. Mason's ultimate goal is a meeting with the artist, but speaking to Ai, who is under house arrest and forbidden to talk with foreign journalists, is not easy. In fact, just finding his world-famous art studio is not easy. On his journey, Mason uncovers some of the simmering societal tensions in modern day, urban China. --Benjamin Moebius

About the Author
Wyatt Mason is a contributing writer for the New York Times Magazine and a contributing editor at Harper's. He won a National Magazine Award in 2006 and teaches at Bard College.

From AudioFile

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6 of 6 people found the following review helpful.
Finding the Strangenesses
By JackReads
Wyatt Mason begins "The Danger Artist" in late July one month after Ai Weiwei was released from the Chinese authority. Knowing the likelihood of speaking with Ai was slim to none, the narrative is formed around the impossible journey of finding Ai. Seemingly defeated at the outset, the journey attempts "to see enough of the world he [Ai] called his own to make sense of a matter of no small interest: Why it is that not a few people of discernment now consider him to be one of the most significant artists working today."

In the short ten days of Mason's visit to Beijing, he indeed sees enough of Beijing to capture the city's strangeness or "strangenesses." On the common uncommon qualities we hear about Beijing--the unbearable smog, heat, vastness and sheer enormity--Mason's telling is original and beautifully seen. And despite the gravity of subject, levity is not lacking in the odd situations Mason finds himself in, from an `unprincipled paparazzo' diner stakeout to an awkward spa moment involving the question "you want massage...here."

These vignettes when interwoven communicate the crux of China's strangeness, that elusive strangeness of life in a totalitarian state. It's not so much that Mason writes it directly, but in each vignette the reader gets more a sense of the muted yet pervasive illogic, double-talk, and absurdity in daily happenings. It's like when Mason arrives at the final stop, and says "We were here. And yet we were not."

In feeling some small part of Ai's world, does the difficultly of seeing through all the strangenesses become apparent and does Ai's insistence on reality and fact in his art truly become extraordinary. A wonderfully written and thoughtful essay--I highly recommend it.

5 of 5 people found the following review helpful.
Whatever we think is meaningful is somehow dangerous
By savonarola
Wyatt Mason arrived in Beijing a month after the Chinese artist, dissident, gambler, provocateur and conscientious objector via Twitter Ai Weiwei was released from an 81-day detention by police and forbidden from speaking to the international press. This gripping, furious, and beautifully reported dispatch from the maw of the simmering megalopolis (Mao's credo "no construction without destruction" has found its ultimate expression in the city's current building boom) tells the story of Mason's careful dance to meet his subject--Ai Weiwei's studio is watched by cameras and his every move, both online and off, is monitored--and his encounters with a society where everything is furtive, it seems, except consumption. I won't play spoiler here and reveal what happens; but Mason manages to capture, with just a few deftly chosen scenes, the strangeness of life in the hybrid state that the PRC has become, the cost of its repressive human rights policies, and the true value of artistic expression, which is only dimly related to any work's value in the marketplace. This is not your ordinary magazine writing, and it should be required reading for ayone who loves their Chinese-made handhelds and readers. I'm going to tell everyone I know about this Single!

5 of 5 people found the following review helpful.
The Power of Thinking under Dictatorship
By The Jurisprude
I just read Mr. Mason's book on Ai Weiwei the day that Vaclav Havel died, and the parallels are extraordinary. Ai Weiwei is not only one of my favorite artists, which I knew. What I did not know is how courageous he is and how he has become one of the leading political actors in China, someone whose insistence on truth is making him the most dangerous man in China, at least from the perspective of the Chinese Communist Party. He is also one of the most interesting. This is a spectacular book-length essay that is beautifully written and brings you into Ai Weiwei's world slowly and deeply. By the end I was left wanting more. It reminds me of Hannah Arendt's insight, that in dictatorship simply thinking becomes political. The Danger Artist (GQ Books) Highly recommended.

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Sabtu, 17 Maret 2012

[K205.Ebook] Download Circuits, Signals, and Systems for Bioengineers: A MATLAB-Based Introduction (Biomedical Engineering)

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Will be shipped from US. Brand new copy.

  • Sales Rank: #6589903 in Books
  • Published on: 1656
  • Binding: Hardcover

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Kamis, 15 Maret 2012

[W681.Ebook] Download PDF Clinical Research: Concepts and Principles for Advanced Practice Nurses, by Manfred Stommel PhD, Celia E. Wills BSN MS PhD RN

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Clinical Research: Concepts and Principles for Advanced Practice Nurses, by Manfred Stommel PhD, Celia E. Wills BSN  MS  PhD  RN

This unique textbook integrates statistical concepts into evidence-based clinical practice and patient management. Research concepts and techniques are drawn from epidemiology, bio-statistics, and psychometrics, as well as educational and social science research. Clinical examples throughout the text illustrate practical and scientifically sound applications of the concepts. Data tables and research vignettes highlight statistical distributions involving probability. Methods to locate and utilize web-based information relevant to clinical research are discussed, and web URLs are provided. Further learning is encouraged by the inclusion of suggested activities, recommended readings, references, and a comprehensive glossary of research terms. Additional resources are available at a Connection Website, connection.LWW.com/go/stommel.

  • Sales Rank: #1208390 in Books
  • Brand: Brand: LWW
  • Published on: 2003-09-12
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.00" h x 7.25" w x 1.00" l, 1.72 pounds
  • Binding: Paperback
  • 480 pages
Features
  • Used Book in Good Condition

Most helpful customer reviews

1 of 1 people found the following review helpful.
too much too fast
By Avid reader
This book is stronger than tranquilizers if you have trouble sleeping! But that aside, it plows right into discussion without establishing a strong base for new concepts. What descriptions are given feel too abstract to be useful (based on having a teacher later explain and clarify). Many vocabulary terms aren't defined, but rather used in an example. If you don't know the word's meaning to start with, the example is useless. Thank goodness for the glossary, but why should the reader have to spend the entire time flipping back and forth? I don't have any experience with another text, but I feel that this isn't a great book for someone just getting seriously into research. As a graduate student with a strong nursing background, I still found this book very hard to wade through.

0 of 0 people found the following review helpful.
Research Guidelines
By tiffergirl7
This is a very wordy, at times obscure text to read. It contains very detailed descriptions of each method to be utilized for the reader to get a grasp on how to apply the methods in research. Found the text to be rather dry, but perhaps someone more engaged in the material will find it more interesting.

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[W169.Ebook] Free PDF The Industrial Revolution (Milestones in Business History), by Jeff Horn

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The Industrial Revolution (Milestones in Business History), by Jeff Horn

The confluence of developments in technology, labor and management practice, and market expansion in the period from 1760 to 1850 so drastically altered the context of economic relations that, taken together, these changes have earned the name, Industrial Revolution. This book, the first in a series of titles to explore turning points and important events in business history, explains the nature of these changes, how they came about, how people reacted to the new economic environment, and the direct impact that they have had on the way business is conducted today.

This volume will address how the Industrial Revolution played out in Europe, the United States, and the rest of the world, emphasizing the role of the government in both promoting and regulating commerce. It will clarify the important distinctions between the original Industrial Revolution and the second Industrial Revolution (approximately 1850 to the early 20th century), which was characterized by accelerating growth, brought about the introduction of the internal combustion engine, electric power, and other technological and managerial developments. Featuring biographical sketches, photos, a timeline, a glossary of key terms, and excerpts of primary documents, The Industrial Revolution reveals the daily life of the entrepreneurs, bureaucrats, and workers who experienced the dramatic changes in technology, business, and trade, and the resulting changes in society and culture.

  • Sales Rank: #3148113 in Books
  • Published on: 2007-04-30
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.21" h x .50" w x 6.14" l, .97 pounds
  • Binding: Hardcover
  • 192 pages

Review
"Horn explains for the general reader how the Industrial Revolution resulted in the system of trade, conquest and colonization practiced by the West up to the present, how Western domestic practices presaged its behavior internationally, and how Western states worked for or against industrialization. He describes the standards of living during the Industrial Revolution, the theoretical and historical foundations of what became a new economy, the impact of technological improvements and the elaboration of the factory system, the reasons why Britain was the first, the realities of dealing with dominant economic powers, the features of industrialization that led to the new world order, and the dynamics of a system set by supply, demand and fashion." - Reference & Research Book News

About the Author

Jeff Horn is Associate Professor of History at Manhattan College. He serves on the editorial board for the Proceedings of the Western Society for French History and is a book review editor for the on-line discussion group, H-France. He is the author of two monographs and has published widely, both in French and in English, on 18th- and 19th-Century French history and the emergence of the Industrial Revolution. He was co-convenor of Reconceptualizing the Industrial Revolution, an international conference from which an edited volume will be published in 2007.

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Sabtu, 10 Maret 2012

[U538.Ebook] Ebook How to Steal a Dragon's Sword (How To Train Your Dragon)

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Rabu, 29 Februari 2012

[W791.Ebook] Download Ebook The Archaeology of Elam: Formation and Transformation of an Ancient Iranian State (Cambridge World Archaeology), by D. T. Potts

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The Archaeology of Elam: Formation and Transformation of an Ancient Iranian State (Cambridge World Archaeology), by D. T. Potts

Elam was an important state in southwestern Iran from the third millennium BC to the appearance of the Persian Empire and beyond. Less well-known than its neighbors in Mesopotamia, Anatolia, the Levant or Egypt, it was nonetheless a region of extraordinary cultural vitality. This book examines the formation and transformation of Elam's many identities through both archaeological and written evidence, and brings to life one of the most important regions of Western Asia, re-evaluates its significance, and places it in the context of the most recent archaeological and historical scholarship. The new edition includes material from over 800 additional sources, reflecting the enormous amount of fieldwork and scholarship on Iran since 1999. Every chapter contains new insights and material that have been seamlessly integrated into the text in order to give the reader an up-to-date understanding of ancient Elam.

  • Sales Rank: #5143122 in Books
  • Published on: 2015-11-12
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.96" h x 1.30" w x 6.97" l, .0 pounds
  • Binding: Hardcover
  • 488 pages

About the Author
D. T. Potts is Professor of Ancient Near Eastern Archaeology and History at the Institute for the Study of the Ancient World, New York University. He is the editor of The Oxford Handbook of Ancient Iran (2013) and the author of Nomadism in Iran: From Antiquity to the Modern Era (2014), as well as numerous other books and articles in scholarly journals.

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